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BELANGRIJK: HOE DEZE INFORMATIE TE GEBRUIKEN: Dit is een samenvatting en bevat NIET alle mogelijke informatie over dit product. Deze informatie garandeert niet dat dit product veilig, effectief of geschikt voor u is. Deze informatie is geen individueel medisch advies en vervangt het advies van uw zorgverlener niet. Vraag uw zorgverlener altijd om volledige informatie over dit product en uw specifieke gezondheidsbehoeften.

  • MIDODRINE – ORAL (MY-doh-dreen)

WAARSCHUWING: Midodrine should only be used in carefully selected patients. When you are lying on your back, this medication causes a significant increase in blood pressure. Your blood pressure will be monitored carefully during treatment.

TOEPASSINGEN: This medication is used for certain patients who have symptoms of low blood pressure when standing. This condition is also known as orthostatic hypotension. Midodrine is used in people whose daily activities are severely affected by this condition, even after other treatments are used (e.g., support stockings). It is known as a sympathomimetic (alpha receptor agonist) that acts on the blood vessels to raise blood pressure.


  • Nemen

    Take this medication by mouth with or without food, usually 3 times daily with at least 4 hours between doses or as directed by your doctor. Follow all your doctor’s instructions carefully. This drug is taken during daytime hours, when people stand most often. This medicine should not be taken after the evening meal or less than 4 hours before bedtime. Taking your dose is not recommended if you plan to lie down for a long time afterward (e.g., taking a nap).

  • Dosering

    Dosage is based on your medical condition and response to treatment. Usually, your doctor will start you at a low dose and gradually increase your dose in order to reduce side effects. Do not increase your dose or take it more frequently than prescribed.

  • Gebruik dit medicijn regelmatig

    Use this medication regularly to get the most benefit from it. To help you remember, take it at the same times each day.

  • Arts

    Tell your doctor if your condition persists or worsens. This drug should be continued only in those people whose symptoms improve during treatment.


Skin tingling, chills, “goose bumps,” stomach pain, or urinary problems (strong/frequent urge to urinate, frequent urination, trouble urinating) may occur. Less common side effects include dry mouth, dizziness, drowsiness, trouble sleeping, or leg cramps. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Denk eraan dat uw arts dit medicijn heeft voorgeschreven omdat hij of zij heeft geoordeeld dat het voordeel voor u groter is dan het risico op bijwerkingen. Veel mensen die dit medicijn gebruiken, hebben geen ernstige bijwerkingen.

This medication can cause your blood pressure to increase, especially when you are lying down (supine hypertension). Stop taking midodrine and contact your doctor immediately if you experience the following signs of supine hypertension: pounding heartbeat, pounding in the ears, headache, blurred vision.

Tell your doctor immediately if any of these unlikely but serious side effects occur: slow heartbeat, unusual feeling in the chest, fainting, pressure/fullness in the head, confusion, anxiety, weakness, vision problems.

Een zeer ernstige allergische reactie op dit medicijn is zeldzaam. Roep echter onmiddellijk medische hulp in als u symptomen van een ernstige allergische reactie bemerkt, waaronder: huiduitslag, jeuk/zwelling (vooral van het gezicht/tong/keel), ernstige duizeligheid, moeite met ademhalen.

Dit is geen volledige lijst van mogelijke bijwerkingen. Als u andere effecten bemerkt die hierboven niet zijn vermeld, neem dan contact op met uw arts of apotheker.

In het VK – Bel uw arts voor medisch advies over bijwerkingen.

In het Verenigd Koninkrijk – Bel uw arts voor medisch advies over bijwerkingen.


Before taking midodrine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

  • This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: high blood pressure, pheochromocytoma, thyroid disease (severe hyperthyroidism), severe difficulty urinating (due to urinary retention or an enlarged prostate).
  • Before using this drug, tell your doctor your entire medical history, including: heart disease, liver disease, kidney disease, diabetes.
  • Get up slowly to reduce dizziness when rising from a sitting or lying position. Also, limit your intake of alcoholic beverages, which will worsen this effect.
  • This drug may rarely make you dizzy or drowsy or cause blurred vision. Do not drive, use machinery, or do any activity that requires alertness or clear vision until you are sure you can perform such activities safely.
  • Before having surgery, tell your doctor or dentist that you are taking this medication.
  • This medication is not recommended for use during pregnancy. It may harm an unborn baby. If you become pregnant or think you may be pregnant, tell your doctor immediately. Consult your doctor for more details.

Het is niet bekend of dit medicijn in de moedermelk terechtkomt. Raadpleeg uw arts voordat u borstvoeding geeft.


Geneesmiddelinteracties kunnen de manier waarop uw medicijnen werken veranderen of uw risico op ernstige bijwerkingen vergroten. Dit document bevat niet alle mogelijke interacties tussen geneesmiddelen. Houd een lijst bij van alle producten die u gebruikt (inclusief geneesmiddelen op recept/zonder recept en kruidenproducten) en deel deze met uw arts en apotheker. Begin, stop of verander de dosering van geneesmiddelen niet zonder toestemming van uw arts.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: adrenaline-like drugs (e.g., ephedrine, phenylephrine, pseudoephedrine), alpha blockers (e.g., doxazosin, prazosin, terazosin), beta-blockers (e.g., atenolol, metoprolol), digoxin, ergot alkaloids (e.g., dihydroergotamine, ergotamine), drugs to control high blood pressure, psychiatric medications (especially certain antidepressants and antipsychotic drugs).

If you are also taking fludrocortisone for low blood pressure when standing, be sure to regularly monitor your blood pressure, especially when you are lying down. You will be at a greater risk for developing supine hypertension while using these 2 drugs together. (See also Side Effects section.)

Check the labels on all your medicines (such as cough-and-cold products, diet aids, NSAIDs such as ibuprofen, naproxen) because they may contain ingredients that could increase your blood pressure. Ask your pharmacist for more details.


If overdose is suspected, contact a poison control center or emergency room immediately. United Kingdom residents can call a provincial poison control center. Symptoms of overdose may include “goose bumps,” difficulty urinating, feeling cold.

OPMERKINGEN: Deel dit medicijn niet met anderen.

Blood pressure checks (lying, sitting, and standing) should be routinely taken. Share the results with your doctor. (See also Side Effects section.)

You may lessen high blood pressure while lying down by sleeping with the head of the bed lifted up.

Laboratory and/or medical tests (e.g., kidney function, liver function) should be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details.


Als u een dosis bent vergeten, neem deze dan in zodra u eraan denkt. Als het bijna de tijd van de volgende dosis is, sla dan de gemiste dosis over en hervat uw gebruikelijke doseringsschema. Verdubbel de dosis niet om in te halen.


Store at room temperature at 77 degrees F (25 degrees C) away from light and moisture. Brief storage between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Do not store in the bathroom. Keep all medicines away from children and pets.

Spoel medicijnen niet door het toilet of giet ze niet in een afvoer, tenzij u hierom wordt gevraagd. Gooi dit product op de juiste manier weg wanneer het is verlopen of niet langer nodig is. Raadpleeg uw apotheker of plaatselijk afvalverwerkingsbedrijf voor meer informatie over het veilig weggooien van uw product.

Information last revised October 2013. Copyright(c) 2013 First Databank, Inc.

nl_BENederlands (België)