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IMPORTANTE: COME USARE QUESTE INFORMAZIONI: Questo è un riassunto e NON contiene tutte le informazioni possibili su questo prodotto. Queste informazioni non garantiscono che questo prodotto sia sicuro, efficace o appropriato per te. Queste informazioni non costituiscono un consiglio medico individuale e non sostituiscono il parere del proprio medico. Chiedete sempre al vostro medico curante informazioni complete su questo prodotto e le vostre specifiche esigenze di salute.

  • MIDODRINE – ORAL (MY-doh-dreen)
  • MARCHIO COMUNE(I) – ProAmatine

AVVERTIMENTO: Midodrine should only be used in carefully selected patients. When you are lying on your back, this medication causes a significant increase in blood pressure. Your blood pressure will be monitored carefully during treatment.

USI: This medication is used for certain patients who have symptoms of low blood pressure when standing. This condition is also known as orthostatic hypotension. Midodrine is used in people whose daily activities are severely affected by this condition, even after other treatments are used (e.g., support stockings). It is known as a sympathomimetic (alpha receptor agonist) that acts on the blood vessels to raise blood pressure.


  • Prendere

    Take this medication by mouth with or without food, usually 3 times daily with at least 4 hours between doses or as directed by your doctor. Follow all your doctor’s instructions carefully. This drug is taken during daytime hours, when people stand most often. This medicine should not be taken after the evening meal or less than 4 hours before bedtime. Taking your dose is not recommended if you plan to lie down for a long time afterward (e.g., taking a nap).

  • Dosaggio

    Dosage is based on your medical condition and response to treatment. Usually, your doctor will start you at a low dose and gradually increase your dose in order to reduce side effects. Do not increase your dose or take it more frequently than prescribed.

  • Utilizzare questo farmaco regolarmente

    Use this medication regularly to get the most benefit from it. To help you remember, take it at the same times each day.

  • Medico

    Tell your doctor if your condition persists or worsens. This drug should be continued only in those people whose symptoms improve during treatment.


Skin tingling, chills, “goose bumps,” stomach pain, or urinary problems (strong/frequent urge to urinate, frequent urination, trouble urinating) may occur. Less common side effects include dry mouth, dizziness, drowsiness, trouble sleeping, or leg cramps. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Ricorda che il tuo medico ha prescritto questo farmaco perché ha ritenuto che il beneficio per te sia maggiore del rischio di effetti collaterali. Molte persone che usano questo farmaco non hanno gravi effetti collaterali.

This medication can cause your blood pressure to increase, especially when you are lying down (supine hypertension). Stop taking midodrine and contact your doctor immediately if you experience the following signs of supine hypertension: pounding heartbeat, pounding in the ears, headache, blurred vision.

Tell your doctor immediately if any of these unlikely but serious side effects occur: slow heartbeat, unusual feeling in the chest, fainting, pressure/fullness in the head, confusion, anxiety, weakness, vision problems.

Una reazione allergica molto grave a questo farmaco è rara. Tuttavia, rivolgersi immediatamente a un medico se nota qualsiasi sintomo di una grave reazione allergica, inclusi: eruzione cutanea, prurito/gonfiore (soprattutto del viso/lingua/gola), forti capogiri, difficoltà respiratorie.

Questo non è un elenco completo dei possibili effetti collaterali. Se nota altri effetti non elencati sopra, contatti il medico o il farmacista.

Nel Regno Unito - Chiama il tuo medico per un consiglio medico sugli effetti collaterali.

Nel Regno Unito - Chiama il tuo medico per un consiglio medico sugli effetti collaterali.


Before taking midodrine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

  • This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: high blood pressure, pheochromocytoma, thyroid disease (severe hyperthyroidism), severe difficulty urinating (due to urinary retention or an enlarged prostate).
  • Before using this drug, tell your doctor your entire medical history, including: heart disease, liver disease, kidney disease, diabetes.
  • Get up slowly to reduce dizziness when rising from a sitting or lying position. Also, limit your intake of alcoholic beverages, which will worsen this effect.
  • This drug may rarely make you dizzy or drowsy or cause blurred vision. Do not drive, use machinery, or do any activity that requires alertness or clear vision until you are sure you can perform such activities safely.
  • Prima di sottoporsi a un intervento chirurgico, informi il medico o il dentista che stai assumendo questo farmaco.
  • This medication is not recommended for use during pregnancy. It may harm an unborn baby. If you become pregnant or think you may be pregnant, tell your doctor immediately. Consult your doctor for more details.

Non è noto se questo farmaco passi nel latte materno. Consultare il medico prima di allattare.


Le interazioni farmacologiche possono modificare il modo in cui funzionano i farmaci o aumentare il rischio di gravi effetti collaterali. Questo documento non contiene tutte le possibili interazioni farmacologiche. Tieni un elenco di tutti i prodotti che usi (inclusi farmaci da prescrizione/non soggetti a prescrizione e prodotti a base di erbe) e condividilo con il tuo medico e farmacista. Non iniziare, interrompere o modificare il dosaggio di alcun medicinale senza l'approvazione del medico.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: adrenaline-like drugs (e.g., ephedrine, phenylephrine, pseudoephedrine), alpha blockers (e.g., doxazosin, prazosin, terazosin), beta-blockers (e.g., atenolol, metoprolol), digoxin, ergot alkaloids (e.g., dihydroergotamine, ergotamine), drugs to control high blood pressure, psychiatric medications (especially certain antidepressants and antipsychotic drugs).

If you are also taking fludrocortisone for low blood pressure when standing, be sure to regularly monitor your blood pressure, especially when you are lying down. You will be at a greater risk for developing supine hypertension while using these 2 drugs together. (See also Side Effects section.)

Check the labels on all your medicines (such as cough-and-cold products, diet aids, NSAIDs such as ibuprofen, naproxen) because they may contain ingredients that could increase your blood pressure. Ask your pharmacist for more details.


If overdose is suspected, contact a poison control center or emergency room immediately. United Kingdom residents can call a provincial poison control center. Symptoms of overdose may include “goose bumps,” difficulty urinating, feeling cold.

APPUNTI: Non condividere questo farmaco con altri.

Blood pressure checks (lying, sitting, and standing) should be routinely taken. Share the results with your doctor. (See also Side Effects section.)

You may lessen high blood pressure while lying down by sleeping with the head of the bed lifted up.

Laboratory and/or medical tests (e.g., kidney function, liver function) should be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details.


Se dimentica una dose, la prenda non appena se ne ricorda. Se è vicino all'ora della dose successiva, salti la dose dimenticata e riprendi il consueto schema posologico. Non raddoppiare la dose per recuperare.


Store at room temperature at 77 degrees F (25 degrees C) away from light and moisture. Brief storage between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Do not store in the bathroom. Keep all medicines away from children and pets.

Non gettare i farmaci nel water o versarli in uno scarico a meno che non venga richiesto di farlo. Eliminare correttamente questo prodotto quando è scaduto o non è più necessario. Consultare il farmacista o l'azienda locale per lo smaltimento dei rifiuti per maggiori dettagli su come eliminare in sicurezza il prodotto.

Information last revised October 2013. Copyright(c) 2013 First Databank, Inc.