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IMPORTANT : COMMENT UTILISER CES INFORMATIONS : Ceci est un résumé et ne contient PAS toutes les informations possibles sur ce produit. Ces informations ne garantissent pas que ce produit est sûr, efficace ou approprié pour vous. Ces informations ne constituent pas un avis médical individuel et ne remplacent pas les conseils de votre professionnel de la santé. Demandez toujours à votre professionnel de la santé des informations complètes sur ce produit et vos besoins spécifiques en matière de santé.

  • MIDODRINE – ORAL (MY-doh-dreen)
  • NOM(S) DE MARQUE COMMUN(S) – ProAmatine

ATTENTION: Midodrine should only be used in carefully selected patients. When you are lying on your back, this medication causes a significant increase in blood pressure. Your blood pressure will be monitored carefully during treatment.

LES USAGES: This medication is used for certain patients who have symptoms of low blood pressure when standing. This condition is also known as orthostatic hypotension. Midodrine is used in people whose daily activities are severely affected by this condition, even after other treatments are used (e.g., support stockings). It is known as a sympathomimetic (alpha receptor agonist) that acts on the blood vessels to raise blood pressure.


  • Prendre

    Take this medication by mouth with or without food, usually 3 times daily with at least 4 hours between doses or as directed by your doctor. Follow all your doctor’s instructions carefully. This drug is taken during daytime hours, when people stand most often. This medicine should not be taken after the evening meal or less than 4 hours before bedtime. Taking your dose is not recommended if you plan to lie down for a long time afterward (e.g., taking a nap).

  • Dosage

    Dosage is based on your medical condition and response to treatment. Usually, your doctor will start you at a low dose and gradually increase your dose in order to reduce side effects. Do not increase your dose or take it more frequently than prescribed.

  • Utilisez ce médicament régulièrement

    Use this medication regularly to get the most benefit from it. To help you remember, take it at the same times each day.

  • Médecin

    Tell your doctor if your condition persists or worsens. This drug should be continued only in those people whose symptoms improve during treatment.


Skin tingling, chills, “goose bumps,” stomach pain, or urinary problems (strong/frequent urge to urinate, frequent urination, trouble urinating) may occur. Less common side effects include dry mouth, dizziness, drowsiness, trouble sleeping, or leg cramps. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

N'oubliez pas que votre médecin vous a prescrit ce médicament car il a jugé que le bénéfice pour vous est supérieur au risque d'effets secondaires. De nombreuses personnes utilisant ce médicament n'ont pas d'effets secondaires graves.

This medication can cause your blood pressure to increase, especially when you are lying down (supine hypertension). Stop taking midodrine and contact your doctor immediately if you experience the following signs of supine hypertension: pounding heartbeat, pounding in the ears, headache, blurred vision.

Tell your doctor immediately if any of these unlikely but serious side effects occur: slow heartbeat, unusual feeling in the chest, fainting, pressure/fullness in the head, confusion, anxiety, weakness, vision problems.

A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

Ce n'est pas une liste complète des effets secondaires possibles. Si vous remarquez d'autres effets non mentionnés ci-dessus, contactez votre médecin ou votre pharmacien.

Au Royaume-Uni - Appelez votre médecin pour obtenir des conseils médicaux sur les effets secondaires.

Au Royaume-Uni - Appelez votre médecin pour obtenir des conseils médicaux sur les effets secondaires.


Before taking midodrine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

  • This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: high blood pressure, pheochromocytoma, thyroid disease (severe hyperthyroidism), severe difficulty urinating (due to urinary retention or an enlarged prostate).
  • Before using this drug, tell your doctor your entire medical history, including: heart disease, liver disease, kidney disease, diabetes.
  • Get up slowly to reduce dizziness when rising from a sitting or lying position. Also, limit your intake of alcoholic beverages, which will worsen this effect.
  • This drug may rarely make you dizzy or drowsy or cause blurred vision. Do not drive, use machinery, or do any activity that requires alertness or clear vision until you are sure you can perform such activities safely.
  • Avant de subir une intervention chirurgicale, informez votre médecin ou votre dentiste que vous prenez ce médicament.
  • This medication is not recommended for use during pregnancy. It may harm an unborn baby. If you become pregnant or think you may be pregnant, tell your doctor immediately. Consult your doctor for more details.

On ne sait pas si ce médicament passe dans le lait maternel. Consultez votre médecin avant d'allaiter.


Les interactions médicamenteuses peuvent modifier le mode d'action de vos médicaments ou augmenter votre risque d'effets secondaires graves. Ce document ne contient pas toutes les interactions médicamenteuses possibles. Gardez une liste de tous les produits que vous utilisez (y compris les médicaments sur ordonnance ou en vente libre et les produits à base de plantes) et partagez-la avec votre médecin et votre pharmacien. Ne commencez pas, n'arrêtez pas ou ne modifiez pas la posologie de tout médicament sans l'approbation de votre médecin.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: adrenaline-like drugs (e.g., ephedrine, phenylephrine, pseudoephedrine), alpha blockers (e.g., doxazosin, prazosin, terazosin), beta-blockers (e.g., atenolol, metoprolol), digoxin, ergot alkaloids (e.g., dihydroergotamine, ergotamine), drugs to control high blood pressure, psychiatric medications (especially certain antidepressants and antipsychotic drugs).

If you are also taking fludrocortisone for low blood pressure when standing, be sure to regularly monitor your blood pressure, especially when you are lying down. You will be at a greater risk for developing supine hypertension while using these 2 drugs together. (See also Side Effects section.)

Check the labels on all your medicines (such as cough-and-cold products, diet aids, NSAIDs such as ibuprofen, naproxen) because they may contain ingredients that could increase your blood pressure. Ask your pharmacist for more details.


If overdose is suspected, contact a poison control center or emergency room immediately. United Kingdom residents can call a provincial poison control center. Symptoms of overdose may include “goose bumps,” difficulty urinating, feeling cold.

REMARQUES: Ne pas partager ce médicament avec d'autres.

Blood pressure checks (lying, sitting, and standing) should be routinely taken. Share the results with your doctor. (See also Side Effects section.)

You may lessen high blood pressure while lying down by sleeping with the head of the bed lifted up.

Laboratory and/or medical tests (e.g., kidney function, liver function) should be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details.


Si vous oubliez une dose, prenez-la dès que vous vous en souvenez. S'il est presque l'heure de la dose suivante, sautez la dose oubliée et reprenez votre schéma posologique habituel. Ne doublez pas la dose pour vous rattraper.


Store at room temperature at 77 degrees F (25 degrees C) away from light and moisture. Brief storage between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Do not store in the bathroom. Keep all medicines away from children and pets.

Ne jetez pas les médicaments dans les toilettes ou ne les versez pas dans un drain à moins d'y être invité. Jeter correctement ce produit lorsqu'il est périmé ou qu'il n'est plus nécessaire. Consultez votre pharmacien ou votre entreprise locale d'élimination des déchets pour plus de détails sur la façon de jeter votre produit en toute sécurité.

Information last revised October 2013. Copyright(c) 2013 First Databank, Inc.