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IMPORTANT : COMMENT UTILISER CES INFORMATIONS : Ceci est un résumé et ne contient PAS toutes les informations possibles sur ce produit. Ces informations ne garantissent pas que ce produit est sûr, efficace ou approprié pour vous. Ces informations ne constituent pas un avis médical individuel et ne remplacent pas les conseils de votre professionnel de la santé. Demandez toujours à votre professionnel de la santé des informations complètes sur ce produit et vos besoins spécifiques en matière de santé.

  • PRAMIPEXOLE – ORAL (pram-ih-PEX-ole)
  • NOM(S) DE MARQUE COMMUN(S) – Mirapex

USAGE:

Pramipexole is used alone or with other medications to treat Parkinson’s disease. It can improve your ability to move and decrease shakiness (tremor), stiffness, slowed movement, and unsteadiness. It may also decrease the number of episodes of not being able to move (“on-off syndrome”).

This medication is also used to treat a certain medical condition (restless legs syndrome – RLS) that causes an unusual urge to move the legs. Symptoms usually occur at night along with uncomfortable/unpleasant feelings in the legs. This medication can decrease these symptoms and thereby improve sleep.

Pramipexole is a dopamine agonist that works by helping to restore the balance of a certain natural substance (dopamine) in the brain.

COMMENT UTILISER?:

Temps nécessaire : 00 jours 00 heures 05 minutes

Read the Patient Information Leaflet provided by your pharmacist before you start taking pramipexole and each time you get a refill. If you have any questions, consult your doctor or pharmacist.

  1. Prendre

    Take this medication by mouth with or without food, as directed by your doctor. Taking this medication with food may reduce nausea. To decrease the risk of side effects (e.g., drowsiness, low blood pressure) when you first start taking pramipexole, your doctor will slowly increase your dosage until the best dose for you is reached. Take this medication as prescribed. Do not increase your dose or take it more often than directed.

  2. Utilisez ce médicament régulièrement

    Use this medication regularly in order to get the most benefit from it. To help you remember, take it at the same times each day.

  3. Prendre ce médicament

    If you stop taking this medication for several days, you may need to increase your dose slowly back to your previous dosage. Talk with your doctor about how to restart the medication. Do not stop taking this medication without your doctor's approval. Although very unlikely, if you suddenly stop taking this drug, withdrawal reactions may occur. Such reactions can include fever, muscle stiffness, and confusion. Report any such reactions to your doctor immediately. If you have Parkinson's disease and are stopping regular treatment with this drug, gradually reducing the dosage as directed will help prevent withdrawal reactions. Consult your doctor or pharmacist for more details.

  4. Dosage

    La posologie est basée sur votre état de santé et votre réponse au traitement.

  5. Médecin

    It may take a few weeks for the full effects of this medication to be noticed. Inform your doctor if your symptoms do not improve or if they worsen.

EFFETS SECONDAIRES:

  • La nausée
  • vertiges
  • somnolence
  • troubles du sommeil
  • constipation
  • mal de tête
  • or dry mouth may occur

If these effects persist or worsen, notify your doctor promptly.

N'oubliez pas que votre médecin vous a prescrit ce médicament car il a jugé que le bénéfice pour vous est supérieur au risque d'effets secondaires. De nombreuses personnes utilisant ce médicament n'ont pas d'effets secondaires graves.

Informez immédiatement votre médecin si l'un de ces effets indésirables peu probables mais graves survient :

  • évanouissement
  • mental/mood changes (e.g., confusion, depression, hallucinations, memory problems)
  • increased difficulty moving/walking
  • muscle cramps/spasm
  • agitation
  • diminution de la capacité sexuelle
  • increased shakiness (tremor)/stiffness

Informez immédiatement votre médecin si l'un de ces effets secondaires rares mais très graves survient :

  • gonflement des chevilles/pieds
  • chest pain
  • compulsive behaviors (e.g., pathological gambling)
  • fièvre
  • unusually fast/slow/irregular heartbeat
  • muscle pain/weakness
  • fatigue inhabituelle
  • change in amount of urine
  • changements de vision

Some people taking pramipexole have reported falling asleep suddenly during their usual daily activities (e.g., talking on the phone, driving). In some cases, sleep occurred without any feelings of drowsiness beforehand. This sleep effect may occur any time during treatment with pramipexole, including up to 1 year after starting the medication. Therefore, you should not drive or take part in other possibly dangerous activities until you are certain that this medication will not cause drowsiness or sudden sleep. If you experience increased sleepiness or fall asleep during the day, do not drive or take part in other possibly dangerous activities until you have discussed this effect with your doctor. Your risk is increased with use of alcohol or other medications that can make you drowsy. You may also develop a sudden drop in blood pressure, which can cause dizziness, nausea, sweating, and fainting. This is more likely when you are first starting the medication, when your dose is increased, or when you get up suddenly. To lower your risk, get up slowly from a sitting or lying position.

A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include:

  • éruption
  • démangeaisons/gonflement (en particulier du visage/de la langue/de la gorge)
  • étourdissements sévères
  • difficulté à respirer

Ce n'est pas une liste complète des effets secondaires possibles. Si vous remarquez d'autres effets non mentionnés ci-dessus, contactez votre médecin ou votre pharmacien.

Au Royaume-Uni - Appelez votre médecin pour obtenir des conseils médicaux sur les effets secondaires.

PRÉCAUTIONS:

Before taking pramipexole, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

  1. Before using this medication, tell your doctor or pharmacist your medical history, especially of: low blood pressure, heart problems (e.g., irregular heartbeat, heart failure), kidney problems, mental/mood disorders (e.g., confusion, hallucinations, psychosis, schizophrenia), sleep disorder (e.g., sleep apnea, narcolepsy).
  2. This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages.
  3. To minimize dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.
  4. Kidney function declines as you grow older. This medication is removed by the kidneys. Therefore, elderly people may be at a greater risk for side effects such as dizziness and hallucinations while using this drug.
  5. Pendant la grossesse, ce médicament ne doit être utilisé qu'en cas de nécessité absolue. Discutez des risques et des avantages avec votre médecin.

This drug may pass into breast milk and could have undesirable effects on a nursing infant. It may also affect milk production. Therefore, breast-feeding is not recommended while using this drug. Consult your doctor before breast-feeding.

INTERACTIONS MÉDICAMENTEUSES :

Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with them first.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially:

  • antipsychotics (e.g., chlorpromazine, haloperidol, thiothixene)
  • cimetidine
  • metoclopramide

If you are taking levodopa or a carbidopa/levodopa combination, your doctor may direct you to decrease your levodopa dose after you start taking pramipexole.

Tell your doctor or pharmacist if you also take drugs that cause drowsiness such as certain antihistamines (e.g., diphenhydramine), anti-seizure drugs (e.g., carbamazepine), medicine for sleep or anxiety (e.g., alprazolam, diazepam, zolpidem), muscle relaxants, narcotic pain relievers (e.g., codeine), psychiatric medicines (e.g., risperidone, amitriptyline, trazodone).

Check the labels on non-prescription medications for heartburn/upset stomach. They may contain cimetidine, which can affect the level of pramipexole in your body. Also check the labels on all your medicines (e.g., allergy, cough-and-cold products) because they may contain drowsiness-causing ingredients. Ask your pharmacist about the safe use of those products.

Ce document ne contient pas toutes les interactions possibles. Par conséquent, avant d'utiliser ce produit, informez votre médecin ou votre pharmacien de tous les produits que vous utilisez. Gardez une liste de tous vos médicaments avec vous et partagez-la avec votre médecin et votre pharmacien.

SURDOSAGE :

If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline. Canadian residents should call their local poison control center directly.

REMARQUES: Ne pas partager ce médicament avec d'autres.

People with Parkinson’s disease may have an increased risk for developing skin cancer (melanoma). If you are taking this drug to treat Parkinson’s disease, tell your doctor promptly if you notice a change in the appearance or size of moles or other unusual skin changes. Ask your doctor if you should have regular skin exams.

DOSE OUBLIÉE :

If you miss a dose, take it as soon as you remember unless it is almost time for the next dose. In that case, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

ESPACE DE RANGEMENT:

  • Store at room temperature at 77 degrees F (25 degrees C) away from light and moisture.
  • Brief storage between 59-86 degrees F (15-30 degrees C) is permitted.
  • Conservez tous les médicaments hors de portée des enfants et des animaux de compagnie.
  • Ne jetez pas les médicaments dans les toilettes ou ne les versez pas dans un drain à moins d'y être invité.
  • Jeter correctement ce produit lorsqu'il est périmé ou qu'il n'est plus nécessaire.

Consultez votre pharmacien ou votre entreprise locale d'élimination des déchets pour plus de détails sur la façon de jeter votre produit en toute sécurité.

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